Lectures

Antibiotics course.1-Quinolones : lecture

Contents :-Quinolones and fluoroquinolones.Other quinolones.Basic structure of the quinolones.Mechanism of action.Spectrum of fluroquinolon...

10 Dec 2010 / 0 Comments / Read More »
Notes

Hyperparathyroidism : note

• Hyperparathyroidism results from anincrease in the secretion of PTH (parathyroid hormon)• The most common cause (80% of thecases) is a be...

06 Dec 2010 / 0 Comments / Read More »

Cystic fibrosis : note

• Patients with cystic fibrosissecrete very viscous mucus in the lung andsuffer repeated lung infections.The pancreas is also affected and ...

05 Dec 2010 / 0 Comments / Read More »

Obstructive lung disease : note

• Lung volumes are changeddifferently by restrictive and obstructive disease.• Obstructive lung disease iscommonly associated with smoking ...

01 Dec 2010 / 1 Comments / Read More »

General anesthetic drugs : note

# General anesthetic drugs are :-Inhaled :-  * Halothane.   * Isoflurane.  * Nitrous oxide.Intravenous :-   *...

16 Oct 2010 / 0 Comments / Read More »

Videos

  • How to use a peak flow meter : video

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  • The use and the action of Epipen : video

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  • Understanding of enzymes work : video

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  • Understanding of osmosis : video

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  • Exocitosis and endocitosis through cell membrane : video

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  • The structure of DNA : video

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  • The structure of chromosome : video

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  • Understanding of DNA replication process : video

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  • Understanding of meiosis process : video

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  • Understanding of active transport and Na/K pump : video

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Antibiotics course.1-Quinolones : lecture

Contents :-Quinolones and fluoroquinolones.Other quinolones.Basic structure of the quinolones.Mechanism of action.Spectrum of fluroquinolon...

10 Dec 2010 / 0 Comments / Read More »

Mebendazole (Vermox) : drug card

Drug name # Mebendazole. Brand name # Vermox. Class of drug # Anthelmintic. Indications # Anthelmintic (Pinworms, Roundworms...

07 Dec 2010 / 0 Comments / Read More »

Hepatitis A (HAV): Rapid review

·       Introduction. ·       Signs and symptoms....

28 Dec 2010 / 1 Comments / Read More »

The anatomy of the skeletal muscles : video

* How does skeletal muscle attach to bones ?* What are the parts of the skeletal muscle ?* How does the skeletal m...

18 Jul 2010 / 0 Comments / Read More »

Antibiotics course.1-Quinolones : lecture

Contents :-Quinolones and fluoroquinolones.Other quinolones.Basic structure of the quinolones.Mechanism of action.Spectrum of fluroquinolon...

10 Dec 2010 / 0 Comments / Read More »

Rapid Reviews

Hepatitis A (HAV): Rapid review

·       Introduction. ·       Signs and symptoms....

28 Dec 2010 / 1 Comments / Read More »

The use of muscle relaxants in surgical procedures : rapid review

# introduction* Acetylcholine is a major neurotransmitter in the autonomic nervous system. In the peripheral nervous system, acetylcholine ...

14 Jul 2010 / 0 Comments / Read More »

Gallstones : rapid review

# How are the gallstones formed :-* Bile help the body to digest fat , it is made in the liver , stored in the gallbladder until the body n...

24 Jun 2010 / 0 Comments / Read More »

Lipid lowering agents : rapid review

Preface   Triglycerides:     * main constituent of vegetable oil & animal fat .    * High ...

10 Jun 2010 / 0 Comments / Read More »

Drug cards

Mebendazole (Vermox) : drug card

Drug name # Mebendazole. Brand name # Vermox. Class of drug # Anthelmintic. Indications # Anthelmintic (Pinworms, Roundworms...

07 Dec 2010 / 0 Comments / Read More »

Acyclovir (Zovirax) : drug card

Drug name # Acyclovir. Brand name # Zovirax. Class of drug # Antiviral agent. Indications # Herpes simplex (HSV-1 and HSV-2) ...

11 Oct 2010 / 3 Comments / Read More »

Acetylcysteine ( mucomyst ) : drug card

Drug name # Acetylcysteine. Brand name # Mucomyst. Class of drug # Mucolytic agent.     # antidote. Indi...

04 Oct 2010 / 0 Comments / Read More »

Featured

  • Antibiotics course.1-Quinolones : lecture

    Contents :-Quinolones and fluoroquinolones.Other quinolones.Basic structure of the quinolones.Mechanism of action.Spectrum of fluroquinolon...

  • Mebendazole (Vermox) : drug card

    Drug name # Mebendazole. Brand name # Vermox. Class of drug # Anthelmintic. Indications # Anthelmintic (Pinworms, Roundworms...

  • Acyclovir (Zovirax) : drug card

    Drug name # Acyclovir. Brand name # Zovirax. Class of drug # Antiviral agent. Indications # Herpes simplex (HSV-1 and HSV-2) ...

  • The use of muscle relaxants in surgical procedures : rapid review

    # introduction* Acetylcholine is a major neurotransmitter in the autonomic nervous system. In the peripheral nervous system, acetylcholine ...

10:13 PM | Posted by Unknown

Mebendazole (Vermox) : drug card

Drug name
# Mebendazole.
Brand name
# Vermox.
Class of drug
# Anthelmintic.
Indications
# Anthelmintic (Pinworms, Roundworms, hookworms, whipworms).
# Capillariasis.
Mechanism of action
# Inhibits uptake of glucose and other nutrients
by parasitic helminths.
route / Dosage form
# Route : Oral only.
# Dosage form : Sus:- 20mg/ml,Tab:- 100mg.
Dose
# Pinworms
* Adults, children >12 years: 100 mg as single dose. Repeat in 2 weeks if infection persists. Treat other family members.
# Roundworms, hookworms, whipworms
* 100 mg b.i.d. for 3 days. Repeat dose in 3–4 weeks.
# Capillariasis
* Pediatric: 200 mg b.i.d. for 20 days. Its use in children <2 years is considered a relative contraindication.
Pregnancy / Lactation
# Pregnancy: Category C.
# Lactation: Probably present in minute amounts in breast milk. May continue breastfeeding.
Adverse reactions
# Common: diarrhea, abdominal pain, nausea, vomiting.
# Serious: bone marrow suppression, hepatitis, hypersensitivity reactions.
Important interactions
# Drugs that decrease effects/
toxicity of mebendazole: phenytoin, carbamazepine, cimetidine.
Contraindications / precautions
# Use with caution in patients with liver disease, ulcerative colitis, Crohn’s ileitis.
Other notes
# Food: Take with food.
Practical notes
# Avoid driving and other activities requiring mental alertness or that are potentially dangerous until response to drug is known.
# Patient and family members should shower frequently if
   possible.
# Keep hands away from mouth.
# Keep fingernails short and clean.
# Do not shake bedding as this could result in airborne spread of ova.
# Counsel patient’s family members to check for worm infestation and treat accordingly.
# Disinfect toilet daily; wash all fruits and vegetables; cook all meats and vegetables thoroughly.
# Wear gloves when preparing food.
# Patient and family members should be taught how to avoid
   reinfestation with these worms. The following measures
   should be undertaken to avoid reinfection:
  (1) perianal area should be washed thoroughly;
  (2) hands and fingernails should be cleaned before meals and after defecation;
  (3) undergarments and bedclothes should be changed daily.
# Mebendazole is the drug of choice for whipworm; it can produce up to 70% cure with a single treatment. The cure rate for roundworms, pinworms, and hookworms is 90–100%. The criterion for cure is negative perianal swabs for 7 days.
# For those treated for hookworm and whipworm: it may be necessary to take an iron supplement every day and for 6 months following treatment if anemia is present.
Generic names
# Egypt :Antiver,Vermin,Anthelmin,Mebamox,Verm1.
# KSA :- Vermox,Bendazole,Parazole,wormazole.
# prepared by : Dr.Mohamed Abd Elrahman
# References:  - Handbook of clinical drug data, 10th edition. - Clinician'shandbook of prescription drugs . - Physicians' Drug Manual 2005 Edition . -Egyptian drug index . - Saudi drug index .
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